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Cannabis and Mental Health Conditions

Mental health conditions affect peoples’ thoughts, behaviors, and feelings throughout the U.S. on a daily basis. In fact, one in five adults in our country experiences them each year. One resource in particular that people can utilize for relief is medicinal cannabis. This is especially important to know during the pandemic. One study recently showed that participants “with mental health conditions reported increased medicinal cannabis use by 91% since COVID-19 was declared a pandemic.” So what role does cannabis play when it comes to mental health? Here are a few examples relating to anxiety, PTSD, OCD, and depression:

Calming Anxiety

Anxiety is that nervous feeling you get when dealing with stress and it is completely normal. Persistent anxiety, however, may be the result of a disorder. Research currently shows that while cannabis does not cure people who suffer from anxiety long term, it can help them to calm down in the short term. This depends on a couple of factors including the type of cannabis being used and the dosage. Since THC is a psychoactive compound, a high dose of it could actually worsen your symptoms. A high dose of CBD, on the other hand, can be very relaxing. This is because the endocannabinoid system in our bodies process THC and CBD differently.

Recovering from PTSD

Post-traumatic stress disorder (PTSD) is a condition that stems from a horrible event in life, causing nightmares, panic attacks, and fear in general. Those with PTSD can look to cannabis as a way to help them sleep better, remove pain, and calm their anxiety like we mentioned previously. Another recent study completed by Washington State University states that “people suffering from post-traumatic distress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term.” Even short-term results are helpful when it comes to recovery.

Coping with OCD

OCD, or obsessive-compulsive disorder, “causes repeated unwanted thoughts or sensations (obsessions) or the urge to do something over and over again (compulsions).” We already know that the endocannabinoid system affects our anxiety, but it also plays a role in repetitive behaviors. Since cannabinoids like THC and CBD bind with CB1 and CB2 receptors, the obsessions and compulsions in this part of the brain can be reduced.

Handling Depression

If you are suffering from depression then you might notice negative moods, a decrease in your typical energy levels, or even suicidal thoughts. This condition affects one in 15 adults and can happen at any point in your life. Luckily, cannabis can help alleviate these feelings. In 2018, a study in the Journal of Affective Disorders showed that “medical cannabis users perceived a 50% reduction in depression.” It actually only took “two puffs” to decrease depression in this case. Even “baseline symptoms of depression (but not anxiety or stress) appeared to be exacerbated across time.” This proves that cannabis may be right for you if you are experiencing depression.

Research Continues to Gain Traction

While there is still a lot to learn about cannabis’s impact on mental health conditions, research is continuing to discover the important do’s and do not’s of treatment methods. A find like how particular dosages of each cannabinoid can result in completely different effects is a huge step in the right direction. For now, the best advice we can give is to speak to your doctor about medicinal cannabis as you may be eligible to apply for a Missouri medical marijuana card.

North Dispensaries wants to help patients live their best lives through relief that medical marijuana offers. We’re still in the process of opening but for now, check out our website for helpful videos and other informative blog posts. We’re beyond excited to fill your prescription one day soon!


Demystifying Missouri Medical Marijuana Equivalency Units (MMEs)

If you’ve received your medical marijuana license, then you should know that you’re allowed to purchase up to four ounces of dried cannabis per month*. This limit is straightforward if you’re just planning on purchasing flower. But, it gets more complex if you plan on purchasing concentrates or infused products.

How many ounces of dried cannabis are in a tincture/oil or edible?

Thankfully, the state has published a conversion chart to help us compare apples to apples. In this case, they are called Missouri Marijuana Equivalency Units. This chart can be used to convert cannabis products to MMEs.

You can download a wallet-sized version of this chart through the Missouri Department of Health and Senior Services.

How will you know if your purchase is within the legal limit?

It’s your dispensary’s responsibility to communicate your purchase amounts with the state’s tracking system, METRC. Dispensaries will work with METRC to ensure that you do not exceed your purchase limits for any 30-day period. You don’t need to worry about accidentally purchasing more than 32 MMEs per month as your dispensary will prohibit you from purchasing more than this amount.

However, in addition to setting a limit of how much product you can purchase in a 30-day period, the state also sets limits on how much product you can have on hand at any given time. For this reason, we recommend keeping track of how many MMEs you have in your possession.

The average patient can possess a two-month supply of cannabis, which translates to 8 ounces of dried flower or 64 MMEs. Patients with a cultivator license can possess a three-month supply of cannabis, which translates to 12 ounces of dried flower or 96 MMEs.

Patients with caregivers

Patients with a caregiver cultivating on their behalf are also allowed to possess a three-month supply of cannabis. In this case, possession can be shared between the caregiver and the patient. For instance, a caregiver cultivating on behalf of a patient may possess 48 MMEs and the patient may possess another 48 MMEs. Any combination is considered compliant if the total shared amount of product doesn’t exceed 96 MMEs (12 ounces). It’s also important to note that patients being provided MMEs by their caregiver are not subject to purchase limits. Patients under the care of a caregiver are not purchasing marijuana. Rather, they are purchasing the service of cultivation and processing.

Making your own cannabis products

If you’re planning on making your own concentrates or edibles from flower that you purchase or grow yourself, we recommend labelling your product with the volume or weight and corresponding MMEs in case of a home inspection (for those with cultivator licenses) or a challenge by law enforcement (especially if you plan on transporting home-made edibles).

For more information on MMEs or how to obtain your medical marijuana card, check out the state’s medical marijuana handbook.

*Some patients may be allowed to purchase more than this limit if certified by two physicians: https://health.mo.gov/safety/medical-marijuana/pdf/physician-certification-form-alternative.pdf  


How Long Do Edibles Last?

In order to determine how long the high from an edible lasts, there are a few different factors that need to be identified first. Edibles do not last the same amount of time for every single person and, in addition to that, edibles are dosed differently in each product.

It is also important to remember that eating an edible is not the same thing as smoking or vaping cannabis. When people smoke or vaporize cannabis, it enters their bloodstream and produces an instantaneous high. It also immediately begins working to relieve the symptoms that medicinal cannabis treats. The high from smoking cannabis is also a lot shorter – roughly one to four hours.

Since this isn’t a universal rule and is dependent on many things, let’s look at those different factors and how it might impact our high from eating an edible.

Step One: Identifying the User

The most important question needing to be answered is, “How often do I consume cannabis?” This poses a lot of gray-area solutions. On one hand, those who have never used cannabis at all may feel the effects to be a lot stronger than someone who uses it every day. On the other hand, there is such a thing as an endocannabinoid deficiency, meaning some first-time users don’t feel the effects from any kind of cannabis consumption, edible or otherwise. If you are a first-time user, it may take you using marijuana or CBD multiple times before you feel anything. This is because your endocannabinoid system is not “awake” yet, so to speak.

The previous points aside, an edible is said to last a lot longer if you haven’t eaten anything before the edible. This 2012 study showed that THC and CBD were absorbed much quicker on empty stomachs than those participants who had a full stomach. There are other factors that can impact an edible high, too, like how much coffee or caffeine you had that day, your stress levels, and other medications you may be taking.

Step Two: Identifying the Dosage

Remember that a CBD edible will present itself differently than an edible that has THC, too. CBD edibles do not create that “head high” that THC edibles do. CBD edibles will make you feel more relaxed, but relaxation of the body only. Edibles that also have THC will also allow your mind to be impacted. A lot of people start their days with a THC edible so they can have a stimulated mind all day long, while others prefer a CBD edible. CBD edibles are especially useful for sleep if it is timed properly.

THC edibles can have as little as 1 milligram of THC, all the way up to 100 milligrams. Some brands even claim to go above 100 milligrams of THC. An edible with 1 milligram of THC will metabolize in the body much quicker than an edible with 100 milligrams of THC; therefore, the edible lasts for a much shorter period of time. The dosage options for CBD are pretty similar to the options for a THC edible. The key to creating a good experience using an edible is to start low and go slow. Wait and see how your body reacts before reaching for another infused gummy bear or brownie. As we mentioned above, it can take up to four hours for edibles to reach their peak in some cases. This is why it is important to really give your body time to react to the medicine it has been given before deciding to take more.


Cannabis Strains: Indica vs. Sativa

As North prepares to open our first Missouri dispensary, we understand that not every patient with a recommendation for medicinal cannabis is going to be familiar with the products we will soon provide. For example, did you know that cannabis is available in two different strains? Continue reading to learn more about cannabis indica, cannabis sativa, and how to find the right strain for you.

Cannabis Indica

Indica plants can be identified by their short height and wide, dark green leaves. Usually, they contain more CBD than THC. Patients who choose this particular strain are generally seeking something to relax them before sleep. 

Cannabis Sativa

Sativa plants are known for their height (reaching 12+ feet) and skinny leaves. There is typically more THC than CBD in this strain. Patients seeking more energy and to experience less anxiety during the day will tend to select sativa.

Finding the Right Strain for You

While knowing the difference between indica and sativa gives you a point of reference, there are additional factors to consider when selecting a strain – like their blend of cannabinoids and terpenes. Asking for this information in store or researching it online will give you a better idea on how your body might react to the product.

Cannabinoids

Cannabinoids, or the chemical compounds found in flowering cannabis plants, most commonly include CBD and THC. Each of these provides medicinal benefits, but only THC provides a high. CBD can treat inflammation, nausea, anxiety, and other conditions. THC can treat pain, lack of appetite, glaucoma, and more. Deciding what works best for you will help in selecting a particular strain of cannabis.

Terpenes

Terpenes, or the oily compounds that plants secrete in order to produce a distinct aroma, include myrcene, pinene, limonene, humulene, and linalool. While all of these have their own benefits and aromas, you will be the one who has a particular preference. If you don’t like how a strain smells, switch to a new one.

Sourcing Medicinal Cannabis

After learning about the different strains of cannabis and how their overall composition can impact your experience, the next step is to source. Look into the dispensary itself and find out who grows the cannabis. Cannabis indica is used to the climates of the Middle East while cannabis sativa prefers living in conditions similar to Central America. If they are grown differently, then they will provide varying benefits and have different levels of cannabinoids and terpenes.

Don’t settle for a dispensary that tries to sell you on anything less than the full picture. North will soon be able to recommend the strains that you will get the most out of long-term.


Where Did the Idea that Cannabis Kills Brain Cells Come From?

One of the most common reasons people try to deter others, especially young people, from using cannabis is the idea that cannabis kills brain cells. Children are even taught in educational substance abuse programs to tell their friends, “No, thanks, I’d like to keep all of my brain cells,” preparing themselves for when they would inevitably be peer-pressured by their friends to smoke marijuana.

While there are studies that show heavy cannabis use as an adolescent can change the brain, this idea that cannabis “kills brain cells” was perpetuated by a study conducted by Dr. Robert Heath in 1974. His research explored the effects of high-dosage cannabis exposure on a monkey’s brain. The study reported that structural changes were found in the monkey’s brain cells, not the actual killing of brain cells like people claim.

So Does Cannabis Kill Brain Cells?

The idea that cannabis kills brain cells was hinged off this research by Dr. Heath. The Nixon administration’s National Institute of Drug Abuse (NIDA) used this study as their “cannabis kills brain cells” poster child. Some claim the Nixon administration even paid Dr. Heath to create these results, which at this point doesn’t hold much weight.

Regardless of the Nixon administration’s monetary involvement, there just aren’t any additional studies to back up the idea that cannabis kills brain cells other than Dr. Heath’s experiment. In fact, more recent studies have conflicted with this idea entirely. Dr. William Slikker of the National Center of Toxicological Research exposed monkeys to cannabis in high doses for one year. The study reads, “In the monkey brain, we found no alterations in the concentration of neurotransmitters in caudate nucleus, frontal cortex, hypothalamus or brain stem.”

BBC reported in 1974, “[Dr. Heath’s] findings of permanent brain damage have been dismissed by similar, independently conducted studies. But other scientists have argued these methods of animal research are inconclusive.”

What Other Effects Might Cannabis Have on the Brain?

Dr. Mooney of UCLA partnered with Mashable to answer this question. “I don’t think the message to the public should be a dramatic one of cannabis killing brain cells,” said Dr. Mooney. “But I do think it’s important for the public to be aware of a balanced understanding of potential risks of cannabis use.” Dr. Mooney further explained that there is some evidence that marijuana use can negatively impact the brain, but that the need for more research, especially for longtime users, is necessary for drawing a conclusion.

The Effect of Cannabis on a Young Person’s Developing Brain

A huge argument for cannabis use and negative brain changes is that of an adolescent’s use and how it impacts their developing brain. While there are studies that show this is possible, it is also important to point out that it is still inconclusive.

This study, for example, says that “several recent studies have found no evidence that adolescent cannabis use or dependence was associated with IQ decline or neurocognitive performance. A study by Meier et al. of co-twins discordant for cannabis use, found little evidence that cannabis use was associated with impaired executive function between, and suggested that family background may explain the lower neurocognitive performance often reported in cannabis users. Another group investigated associations between adolescent cannabis use and IQ and educational attainment and found no association.”

In other words, some studies find correlations between cannabis use and adolescent cognitive decline, and others do not. This piece of research also emphasizes the need for long-term research on the adolescents who are studied.

The Argument that Cannabis Positively Changes the Brain

Some research actually creates a valid argument for cannabis positively impacting the brain, specifically by igniting the process of neurogenesis or the creation of neurons in the brain. This study says, “A body of data indicates that cannabinoid ligands control cell genesis in the adult brain, regulating cell proliferation and overall neurogenesis in the mammalian brain.” According to this same study, the cannabinoid system plays a central role in adult neurogenesis processes in the hippocampus and lateral ventricles. “Indeed, cannabinoids have clear modulatory roles in adult neurogenesis, probably through activation of both CB1 and CB2 receptors.”

Another study reads, “Recent studies have shown that THC can promote neurogenesis, restore memory, and prevent neurodegenerative processes and cognitive decline in animal models of Alzheimer’s disease. CBD also improves cognition in preclinical models of cognitive impairment in schizophrenia. To reconcile these seemingly contradictory results, it has been suggested that THC modulates memory and cognition in an age- and dose-dependent manner.”

The Conclusion?

Ultimately, the hard science is still unverified. However, we know that cannabis has fewer side effects than many other commonly prescribed drugs. Most human beings can safely collaborate with their doctor to find a cannabis treatment that works for them, without much of a risk.


Methods of Consuming Medical Marijuana

Times are changing and so is the stigma surrounding the consumption of medical marijuana. In the past, people assumed that someone smoking marijuana was doing so illegally. Today, however, there are many patients who need to consume it in a variety of ways for important medicinal reasons. Here are several methods that patients can choose from after receiving their medical marijuana card

Smoking for Instant Relief

One of the most well-known ways to consume medical marijuana, smoking provides relief to the user instantaneously. Start by placing the recommended portion for you into a pipe or onto a piece of paper that can be rolled. Next, simply light the far end and inhale the smoke.

North Fact #1: A major difference between smoking medical marijuana and tobacco is that one comes with helpful cannabinoids and the other addictive nicotine.

Munching on Edibles

If you’re not a smoker, then consider trying edibles to help you recover from your diagnosis. There are many ways to eat these and they all can be quite tasty. Either bake a brownie for yourself or buy items straight from a dispensary like North. Think gummy bears, cookies, and even healthy snacks like nuts. 

North Fact #2: This method will take longer to take effect so let your edible digest before eating more. Do not take anything on an empty stomach.

Infusing Your Favorite Drink

Another flavorful alternative to inhaling, medical marijuana-infused drinks can be more effective than edibles. Drinking soda, coffee, and even tea can make a relaxing experience such as taking your prescription that much better. 

North Fact #3: Cannabinoids in medical marijuana-infused drinks will be absorbed by the body faster than edibles that need to be digested.

Inhaling a Vapor

According to marijuanadoctors.com, “When you vape, you heat marijuana’s active compounds at low temperatures. There’s no burning or combustion at these low temperatures like there is with smoking.” The website continues to explain that CBD oil and raw medical marijuana can be vaped.

North Fact #4: In order to vape, you must also purchase the proper device. North will soon have several options of vape pens for you to choose from at their two Missouri dispensaries.


How to Purchase and Use Cannabis – For Beginners

Step One: Getting a Medical Marijuana Card

Before you can purchase marijuana in Missouri, you must have a medical marijuana patient card that proves you are approved by a physician as well as the state to purchase. We explained in more depth how you can receive a marijuana card here.

Step Two: Choosing a Dispensary

There isn’t a specific dispensary you need to purchase marijuana from if you are a cardholder, except for the requirement of purchasing in Missouri. Unlike a doctor calling a prescription into the pharmacy, your doctor is simply recommending cannabis for you to try. The choice of what product to purchase and where to purchase it is ultimately your decision. Medical marijuana dispensaries operate more like a high-security vitamin and supplement retail store rather than a pharmacy.

That being said, not all dispensaries are the same and it is important that your dispensary of choice meets some criteria before you give them your business.

We would love to see you at North when our dispensaries open this Spring. You can find our dispensaries in Pevely and Hillsboro.

Check the Location of the Dispensary

North, and several other dispensaries will be offering delivery services to their patients, but make sure you are within their delivery zone. If you are picking it up yourself, verify that it is a reasonable distance from your home for you to visit frequently.

Make Sure the Dispensary is Sharing Knowledge and Educating Their Patients

Look on the dispensary’s website – are there online resources for you to pull from? Are they easily able to be contacted? If so, contact them and ask how they plan to help navigate a new marijuana user through the process of purchasing and using it. Your dispensary should always be willing to guide you every step of the way as you learn this information! Check out North’s resource blog for all of your unanswered questions!

Step Three: Brainstorm With Your Budtender and Do Some Research

There are many choices that go into making a decision to purchase a medical marijuana product. The first would be identifying the kind of marijuana you need – either indica or sativa.

The Indica Strain

Indica varieties are usually shorter in size and have shorter growing cycles than their counterpart, sativa. This doesn’t really matter to patients purchasing at the dispensary, but it’s nice to know anyway.

Indica strains are great for people with a need for full-body relaxation. They are great at nighttime and help the user sleep. They usually offer a lot of anti-inflammatory properties and are favored by people who experience pain or other inflammatory conditions like digestive disorders.

The Sativa Strain

Sativa cannabis plants are taller than indicas and they have a longer growing season. People typically use sativa strains when they want to feel uplifted or to stimulate their minds. Sativa strains are great for daytime and morning use because of their energetic effects. A lot of people use a sativa strain before their morning exercise routine or in place of coffee. Sativa strains would be the right choice for someone looking to improve their focus, spark creativity, or energize their spirits!

Selecting the strain you want is only one piece of the puzzle. Now you need to decide how to consume it:

Smoking

Many people are turned off by the idea of smoking. There is conflicting data when it comes to smoking marijuana and the negative effects it can have on your lungs. The reason so many are drawn to it is because it is instantaneous. As soon as you smoke, you begin to feel relief. If you have a condition that causes extreme nausea and you can’t hold anything down in the mornings, smoking might work for you because of its ability to stop nausea in its tracks the moment you use it.

Vaping

Thanks to cool technology, vaping cannabis is an option. It still provides instantaneous relief without combusting the cannabis and creating potentially harmful chemicals. Vaping cannabis still heats it up and allows you to inhale, but it doesn’t burn it.

Edibles + Tinctures

Edibles can be good choices for people looking to seamlessly blend their cannabis consumption into their daily routine without having to take too many extra steps. Edibles can come in a variety of different foods, such as brownies, breakfast bars, and cookies. Different dispensaries will carry different products, so browse around to find one that meets your needs. You can also use a cannabis tincture in your morning coffee or tea.

Head North

North Dispensaries wants to help patients live their best lives through relief that medical marijuana offers. We look forward to seeing you soon!


4 Remarkable Benefits of CBD Oil

The cannabis plant is a unique species that contains many medical benefits through its cannabinoids. A common misconception, however, is that all cannabinoids result in euphoria or a “high” when inhaled, consumed, or directly applied to the skin. Specifically, cannabidiol (CBD) provides several benefits without psychotically impairing patients – especially when diluted with an oil.

What is CBD Oil?

Simply the combination of CBD and an oil. In order for this to happen, CBD must first be separated from the cannabis plant and other cannabinoids such as tetrahydrocannabinol – better known as THC. CBD oil:

Results in Zero Psychoactive Effects

Speaking of THC, it’s the main reason for psychoactive effects that one may experience when using medical marijuana. If you have always wanted to try it for yourself, but don’t have your own Missouri Medical Marijuana Card or are concerned about getting high, try CBD oil instead. There may be tiny amounts of THC in certain CBD oils, but not enough to cause concern.

Provides Pain Relief

Did you know that the human body was designed to receive cannabinoids? If you’re unfamiliar with the endocannabinoid system, North explains its functionality in a previous blog post. Essentially, it helps to regulate pain among other important functions by producing endocannabinoids. After introducing CBD to the body, it will work with those endocannabinoids to reduce inflammation and stop pain in its tracks.

Contains Antioxidant Properties

According to a study, CBD has anti-inflammatory and antioxidant properties. It says that, “analysis of CBD antioxidant activity showed that it can regulate the state of redox directly by affecting the components of the redox system and indirectly by interacting with other molecular targets associated with redox system components.”

Reduces Anxiety

There is also evidence that CBD can calm the central nervous system and reduce anxiety. In 2019, a sample of 72 adults was given CBD for anxiety or sleep-related issues. Of that 72, 57 scored lower after the first month when it came to reporting their anxiety. Additional studies on efficacy and dose are still needed, but this is a great sign for a positive outlook.

Coming Soon to North

After learning about the remarkable benefits of CBD oil, what’s stopping you from relieving your pain or combating your anxiety? North will soon have several options for you to choose from.


What is the Endocannabinoid System?

Not many people know that our bodies have an entire system dedicated to receiving cannabinoids, known as the endocannabinoid system (ECS). It is a widely-studied system that is designed to receive both endocannabinoids and phytocannabinoids.

Our Body is Made to Receive Cannabinoids

Endocannabinoids are compounds naturally produced in the human body (as well as all other vertebrates), while phytocannabinoids are compounds found in many plants, but they are most densely populated in the cannabis plant. Endocannabinoids have been found to be naturally occurring in many places in the human body, including breast milk.

The cannabis plant is composed of phytocannabinoids like CBD, THC, CBG, and they interact with receptors in our body’s endocannabinoid system. There have been over 100 discovered phytocannabinoids. The interaction between cannabinoids and the endocannabinoid system or ECS encourages the body to return to homeostasis and promote an overall sense of well-being in the body.

Two Receptors in the Endocannabinoid System Have Been Discovered

So far, science has only firmly established two receptors in the endocannabinoid system, though there is belief that there could be more, specifically a third receptor.

The known receptors are the CB1 and CB2 receptors. The cannabinoid THC fits the CB1 receptor perfectly. CB1 receptors are mainly found in our brain stem and spinal cord, nervous system, some vital organs, connective tissues, gonads, and glands, though parts of our bodies contain both receptors. The CB1 receptors in our brain stem explains why THC impacts the mind and promotes a gentle psychological altering.

CB2 receptors are mainly found in immune cells and they interact with CBD as opposed to THC. CBG is another phytocannabinoid that has hit the cannabis scene lately. CBG has been shown to also interact primarily with CB2 receptors while providing a non-psychotropic effect.

CB2 receptors are heavily concentrated in the gastrointestinal tract and help to regulate inflammation. This is why CBD and other cannabinoids have been shown to be effective for digestive conditions like ulcerative colitis or Crohn’s disease. This study notes, “Cannabinoids have similarly demonstrated the ability to block spinal, peripheral and gastrointestinal mechanisms that promote pain in headache, fibromyalgia, IBS and related disorders.”

Unlike THC, CBD does not fit the CB2 receptor perfectly. Scientists know that CBD has a strong affinity with both the CB1 and CB2 receptors, but the exact science is still unsettled. It is thought that CBD modifies the receptors’ ability to bind to cannabinoids.

CB1 and CB2 Receptors Help Different Ailments

The idea is that different cannabinoids stimulate the proper endocannabinoid receptors in order to help different ailments. For example, we mentioned the CB2 receptor and how it can benefit digestive ailments when stimulated. It is also anti-inflammatory in nature, making CBD a great remedy for pain. CBD salves are a popular choice among users with chronic pain because the endocannabinoid receptors in the skin are able to receive the CBD and combat inflammation. 

CB1 receptors in the nervous system and brain stem make THC a great medicine for Parkinson’s disease, Alzheimer’s, and others. Many patients attribute THC to the improvement of their symptoms. Watch Larry in this video try medical marijuana for the first time. Larry has Parkinson’s disease and within minutes his tremor dyskinesia subsides.

The Entourage Effect

The CB2 receptor is attractive to researchers because unlike the CB1 receptor, the CB2 receptor does not cause psychotropic effects. This is why CBD is frequently isolated and sold on its own.

However, many researchers and forward-thinking cannabis professionals believe in the “entourage effect,” meaning cannabinoids can work better together. Therefore, isolating CBD or stimulating CB2 receptors by themselves may not produce the same results medically as it would if more of the plant were used. Here is another video, this time of Gary in Colorado. Gary also has Parkinson’s disease and participated in a study exploring the use of CBD to treat it under his doctor’s care. Gary tried it and his tremors did not improve. However, his sleep did and now Gary is a believer in medical marijuana and CBD. He even started growing it and created his own CBD oil.

Knowing what we know about the entourage effect, Gary may have had better luck dissolving his tremors had he tried THC, too. There is new research taking place all of the time trying to learn even more about the endocannabinoid system than we know now. There have been enough studies proving the ECS’s crucial role in our body’s regulatory functions to make a case for medical marijuana.


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